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Scientists for the first time have used CRISPR gene editing to halt the progression of Duchenne muscular dystrophy (DMD) in a large mammal, according to a study by UT Southwestern that provides a strong indication that a lifesaving treatment may be in the pipeline.The research published in Science documents unprecedented improvement in the muscle fibers of dog <a href=https://www.adidas-yeezys.es>adidas yeezy</a> s with DMD 鈥?the most common fatal genetic disease in children, caused by a mutation that inhibits the production of dystrophin, a protein critical for muscle function.Researchers used a single-cut gene-editing technique to restore dystrophin in muscle and heart tissue by up to 92 percent of normal levels. Scientists have estimated a 15 percent threshold is needed to significantly help patients.鈥淐hildren with DMD often die either because their heart loses the strength to pump <a href=https://www.dunks.fr>nike dunk</a> , or their diaphragm becomes <a href=https://www.nbbalance.de>nbbalance</a> too weak to breathe,鈥?said Dr. Eric Olson, Director of UT Southwestern鈥檚 Hamon Center for Regenerative Science and Medicine. 鈥淭hi LAHORE:A 35-year-old rickshaw dri <a href=https://www.campusadidas.fr>adidas campus noir</a> ver died in a road-accident near Badami Bagh police station on Saturday. Police <a href=https://www.campusadidas.fr>adidas campus</a> said Muhammad Ashfaq, son of Muhammad Boota, had an accident near Ring Road when he was hit by a car. <a href=https://www.adidas-samba-adidas.it>adidas samba bianche</a> They said he died on the spot.Published in The Express Tribune, March 27th, 2016.
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Newcastle and Hunter-based researchers have discovered a drug combina yeezys tion that could dramatically improve the life expectancy of children living with brain cancer.DMGs are a fast-growing tumour forming the part of the brain responsible for life sustaining functions like heartbeat, breath dunk nike high ing, swallowing, eyesight, and balance.Palliative radiotherapy is the only established treatment, with families advised their child new balance schuhe is expected to survive nine to 11 months post diagnosis.Want more breaking news?Subscribe to Technology Networks鈥?daily newsletter, delivering breaking science news straight to your inbox every day.Subscribe for FREE ISLAMABAD:The new management of the National Institute of Folk and Traditional Heritage, commonly known as Lok Virsa, the country鈥檚 premier cultural organisation, has started cleansing the organisation of individuals with questionable credentials and under par performance to- put the house in order.The management has removed a senior officer, Yousuf Haroon, fro adidas campus grau m his position and made him an officer on special duty (OSD), a bureaucratic jargon used for punishment.It has been revealed that the cause for this removal was not fulfilling the minimum requirement of a bachelor鈥檚 degree for his post, a source told The Express Tribune with the request for anonymity.Moreover, Lok Virsa鈥檚 notification states that the director, Administration and Accounts, a grade 19 officer, was removed from his post follow samba og adidas ing an internal inquiry.The inquiry report says Haroon has been working with the premier cultural body for over 30 years. He is adidas samba vegan just a matriculate and done a short diploma course while minimum
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Three and a half years after the Boston Marathon bombing, many of the people who lost limbs in the attack are still struggling to heal their physical and emotional wounds.The first feature-length adidas samba rose film about the April 15, 2013 attack and its aftermath, Marathon: The Patriots Day Bombing, which debuts on HBO next week, tells their stories.The documentary opens with graphic video showing the explosion of two homemade pressure cooker bombs in the crowd at the race's finish line, the screams that rent the air and blood nb 993 that coated the sidewalk.Bo adidas campus pink ston Marathon bombing makes way to TV, movie screensIt quickly moves on to focus on the aftermath and the struggles of some of the 264 people injured in the blasts, which killed three people."We didn't want to sanitise it," said Ricki Stern, who directed, wrote and produced the film along with Annie Sundberg."In speaking to the survivors, we asked them how comfortable will you be showing the photographs of you on the ground, showing the video of the American farmers have adopted genetically engineered (GE) crops widely since their introduction in 1996 because of the tangible benefits that biotech varieties deliver.According to the U.S. Departm yeezys 700 ent of Agriculture, U.S. farmers have embraced biotech varieties of soybeans, cotton and corn at the rate of 91 percent, 88 percent and 85 percent, respectively. This is because yeezy agricultural biotechnology allows farmers to grow more food on less land using farming practices that are dunk low more cost effective and environmentally sustainable.Despite these convincing statistics, a report titled Impacts of Genetically Engineered Crops on Pesticide Use in the United States: The First Thirteen Years, claims "farmers are increasingly critical of GE crops."Sharon Bomer Lauritsen, Executive Vice President, Food and Agriculture for the Biotechnology Industry Organization (BIO), issued the following statement in response:"There's no doubt that farmers continue to embrace biotechnology because of the benefits
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DERA GHAZI KHAN:A scuffle took place between lawyers and police in the vicinity of courts in Dera Ghazi Khan on Wednesday.District Bar Association President Ahsan Karim Meerani told The Express Tribune the Kot Mubarak police had detained a suspect Moosa Haiderani Khosa illegally in the lock up. newbalance 530 He added the court bailiff raided the police station and recovered the man.He maintained Moosa was produced before the court which ordered his release. However, he said, 鈥淲hen Moosa came out of the court room along with his lawyers, the Sub-Inspector Allah Dewaya and others tried to arrest him again in another case in the premises of the court.鈥滿eerani pointed out, 鈥淭he lawyers told the police that they could not arrest anyone in the premises of the courts. However, the police did no newbalance 990 t listen and used fo adidas samba nere rce to nab the man.鈥滺e said in the meantime other lawyers also gathered at the spot and a scuffle broke out. He added in protest against the maltreatment meted out by the police, the legal fratern Small changes in the structure of DNA have been implicated in bre new balance 327 ast cancer and other diseases, but they've been extremely difficult to detect -- until now.Using what they describe as a "chemical nose, dunk cacao " UC Riverside chemists are able to "smell" when bits of DNA are folded in unusual ways. Their work designing and demonstrating this system has been published in the journalNature Chemistry."If a DNA sequence is folded, it could prevent the transcription of a gene linked to that particular piece of DNA," said study author and UCR chemistry professor Wenwan Zhong. "In other words, this could have a positive effect by silencing a gene with the potential to cause cancer or promote tumors."Conversely, DNA folding could also have a negative effect."DNA folds could potentially keep viral proteins from being produced to minimize immune response," Zhong said.Studying how these folds might impact living beings, either po yeezy 500 sitively or negatively, first requires scientists to detect their presence. To
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