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Pelago Bioscience AB and AstraZeneca have entered into a 2-year strategic research collaboration and license agreement. The companies will collaborate on specified joint projects and AstraZeneca will also be granted a license to use and apply the Cellular Thermal Shift Assay (CETSA庐) for determination and quantification o dunks nike low f drug鈥搕arget interactions in other AstraZeneca discovery projects.During the collaboration Pelago and AstraZeneca will together develop assay formats and applications yeezy 350 of the CETSA庐 m yeezy slide ethod relevant across the range of AstraZeneca鈥檚 therapeutic areas. The companies will actively share information related to benchmarking and improvement in the use of the technology.鈥淲e are very proud of this collaborative agreement with AstraZeneca. It will allow us to further improve the CETSA method using the knowledge and experience from one of the world鈥檚 largest drug discovery companies鈥?says Michael Dabrowski CEO of Pelago Bioscience.Mike Snowden, Vice President Discovery Sciences Picture shows the ceiling of the Expiatory Church of the "Sagrada Familia" (Holy Family) basilica, designed by Spanish arch newbalance 530 itect Antoni adidas campus homme Gaudi, in new balance uomo Barcelona. PHOTO: AFP

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GENEVA:A Swiss hotel that poste new balance 480 d signs telling Jewish clients to shower before using the po adidas campus grise ol and restricting their access to the facility's freezer has unleash adidas campus beige ed outrage and official complaints from Israel.The Paradies apartment hotel in the Alpine village of Arosa in eastern Switzerland is being accused of anti-Semitism after an outraged guest posted to Facebook a picture of a notice plastered outside the hotel pool."To our Jewish Guests, women, men and children, please take a shower before you go swimming," it said, adding that "If you break the rules I'm forced to [close] the swimming pool for you."A second notice, in the kitchen, meanwhile instructed "Our Jewish guests" that they could only access the facility's freezer between 10 and 11 am and between 4:30 and 5:30 pm."I hope you understand that our team does not like being disturbed all the time," it said.The story quickly made the rounds on social media and was published by Israeli papers, prompting a harsh reaction from Israel The data lie at the heart of translating information from the human genome into successful new drugs in the clinic.The database is hosted by the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI). It was transferred from biotech firm Galapagos NV in July 2008 through a 拢4.7 million Strategic Award from the Wellcome Trust.ChEMBLdb is a unique resource because of its focus on drug discovery and its size: information on an additional 100,000 co asic gels mpounds has been added to the database for its launch, taking the number of small molecules to over 520,000, and now contains over 2.4 million records of their effects on biological systems. The data dunk low include information about how small molecules bind to their targets, how air forces these compounds affect cells and whole organisms, and information on the molecules' absorption, distribution, metabolism, excretion and toxicity. Dr John Overington, leader of the ChEMBL team at EMBL-EBI, said: "We hope ChEMBLdb will assist the tra

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Seven Bridges and SolveBio have announced the integration of their complementary platforms for genomic data analysis. The integration of Seven Bridges鈥?platform for cloud-based biomedical data analysis with SolveBio enables biotech and pharmaceutical researchers to seamlessly transition from the analysis of large NGS datasets to clinical analysis and interpretation, speeding the progress of their precision medicine initiatives. This integration is available in Seven Bridges鈥?Public Apps repository, meaning any joint customer may immediately use this end-to-end workflow.鈥淭hrough the integration of our respective platforms, Seven Bridges and SolveBio are helping to accelerate the pace of precision medicine research from 鈥榖ench to bedside,鈥欌€?said James Sietstra, President of Seven B air forceone ridges. 鈥淪even Bridges brings the scale of the cloud and national-scale genomic datasets, while SolveBio鈥檚 deep knowledge base and context yeezy boost 350 ual intelligence tool chanclas yeezy s help researchers take their work to the next leve NEW DELHI:The Indian government on Saturday named Urjit R. Patel the new governor of the Reserve Bank of India to succeed the popular central banker Raghuram G. Rajan when his term ends in September.Patel, 52, is now one of four deputy governors of the Reserve Bank, running its monetary policy department. He was reappointed in January for a three-year term.His appointment ends weeks of speculation about a successor to Rajan, who announced unexpectedly in June that he planned to adidas samba vegan return to academia.The chief of the Reserve Bank of India is typically chosen by the prime minister in consultation with the finance ministry, making Mr. Patel the first governor to be chosen by the right-w adidas samba verte ing prime minister, Narendra Modi.India's Rajan keeps rates on hold in final move as governorWhile many investors were disappointed in Mr. adidas campus femme Rajan鈥檚 decision to step down, some hope the new appointee will work even harder to cut interest rates.India鈥檚 economy expanded 7.9 percent in the fourth quarter of 2015-16

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Sleeping with a television or light on in the room may be a risk factor for gaining weight or developing obesity, according to scientists at the National Institutes of Health. The research, which was published online June 10 in JAMA Internal Medicine, is the first to find an association between any exposure to artificial light at night while sleeping and weight yeezy boost gain in women. The results suggest that cutting off lights at bedtime could reduce women鈥檚 chances of becoming obese.The research team used questionnaire data fr jordan4 om 43,722 women in the Sister Study, a cohort study that examines risk factors for breast cancer and other diseases. The participants, aged 35-74 years, had no history of cancer or cardiovascular disease a yeezy slide nd were not shift workers, daytime sleepers, or pregnant when the study began. The study questionnaire asked whether the women slept with no light, a small nightlight, light outside of the room, or a light or television on in the room.The scientists used weight, height, PESHAWAR:Lack of proper measures to control the incessant flow of smuggled items through the porous Durand Line from Afghanistan into Pakistan has caused an estimated Rs100 billion loss to the public purse over the last two years alone.Data provided by the customs department shows that 70 per cent of the total goods exported to Afghanistan un samba adidas og der the Afghan Transit Trade (ATT) are smuggled back to Pakistan through various points duly guarded by the law enforcement agencies.Policies needed that promote value additionLast year, more than Rs1 newbalance scarpe 40 billion worth of goods were smuggled back to Pakistan.Talking to The Express Tribune, officials at the department con nb 993 firmed that Khyber-Pakhtunkhwa and Federally Administered Tribal Areas have been generating Rs100 to Rs130 million daily through taxes, much lower than the amount smugglers generate through smuggling across Durand Line.The official claimed that in 2016, around 43,000 containers, with goods worth $2.2 billion, were transported to Afgha