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UT Southwestern Medical Center researchers have found that cancer drugs known as CDK4/6-inhibitors alter th
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ancer cells, revealing a biologic vulnerability that could be exploited for therapeutic gain.Because pancreatic cancer has one of the worse prognoses of any cancer and is the third leading cause of cancer deaths in the U.S., according to the National Cancer Institute, researchers for years have sought to find better treatment options.Last year, the FDA approved the first cyclin-dependent kinase 4/6 (CDK4/6) inhibitor for treating a certain type of advanced breast cancer. This class of drugs has been widely studied in clinical trials for many other types of cancer, including pancreatic cancer. CDK 4/6 inhibitors are cytostatic, meaning they work by preventing cancer cells from growing and dividing.鈥淥n the one hand, that鈥檚 great, because the tumor won鈥檛 grow, but on the other hand, the patient still has a tumor, which will eventually become resistant t
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o t Given the recent headlines of data hacks, one might wonder whether their own personal accounts are safe. Users have been tak
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licly leaked breaches that鈥檚 been illegally obtained and then posted on the web. The site takes data from publicly leaked breaches that鈥檚 been illegally obtained and then posted on the web聽 PHOTO: SCREENGRAB