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A team led by scientists at the UNC School of Medicine discovered yeezy 350 an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability.The scientists, whose study is published inNature Immunology,found that HIV, when it infects immune cells called CD4 T cells, helps fuel its own replication by boosting a key process in the cells' production of chemica air forces l energy. They also found that the diabetes drug metformin inhibits the same process and thereby suppresses HIV replication in these cells, in both cell-culture and mouse experiments."These findings suggest that metformin and other drugs that reduce T cell metabolism might be useful as adjunct therapies for treating HIV," said study co-first author Haitao Guo, PhD, assistant professor in the UNC Department of Genetics at the UNC nike dunk uomo School of Medicine.The co-first author of the study was Qi Wang, PhD, postdoctoral research a MONTREAL:Most o new balance f the hundreds of people streaming over the US border into Canada in recent weeks are asylum-seekers, coming from Syria, Yemen, Turkey or Sudan, according to the United Nations鈥?refugee point man in the country.In an interview, Jean-Nicolas Beuze, the representative in Canada of the United Nations High Commissioner for Refugees (UNHCR), said it was too soon to know whether the cross-border flow of pe boots kaufen ople is an uptick or signals a longer trend.The UNHCR led a mission to the border at Lacolle, about 70km south of Montreal, and the surrounding area, where entire families have been trekking with suitcases and strollers along Roxham Road adidas campus femme that connects to the United States.One in four Canadians support temporary refugee banThe UN mission was coordinated with the border police and the Royal Canadian Mounted Police.For weeks, people have been braving bone-chilling cold to walk across the US border, trudging through snow-covered prairies in the dead of night to make a claim in Ca

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