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Very frequent (may affect more than 1 in 10 folks) injection site reactions (including ache, swelling, redness or itching) respiratory tract infections (together with chilly, runny nostril, sinus infection, pneumonia) headache belly ache nausea and vomiting rash musculoskeletal ache Common (may affect as much as 1 in 10 folks) severe infections (together with blood poisoning and influenza) intestinal infections (together with gastroenteritis) pores and skin infections (together with cellulitis and shingles) ear infections oral infections (including tooth infections and chilly sores) reproductive tract infections urinary tract infection fungal infections joint infections benign tumours pores and skin most cancers allergic reactions (together with seasonal allergy) dehydration mood swings (including depression) anxiety issue sleeping sensation issues similar to tingling, prickling or numbness migraine nerve root compression (including low back pain and leg pain) imaginative and prescient disturbances eye inflammation inflammation of the attention lid and eye swelling vertigo (feeling of dizziness or spinning) sensation of heart beating rapidly hypertension flushing haematoma (collection of blood outdoors of blood vessels) cough asthma shortness of breath gastrointestinal bleeding dyspepsia (indigestion, bloating, coronary heart burn) acid reflux disease illness sicca syndrome (including dry eyes and dry mouth) itching 482 itchy rash bruising inflammation of the pores and skin (such as eczema) breaking of finger nails and toe nails increased sweating hair loss new onset or worsening of psoriasis muscle spasms blood in urine kidney problems chest pain oedema (swelling) fever reduction in blood platelets which will increase danger of bleeding or bruising impaired healing Uncommon (might have an effect on up to 1 in 100 people) opportunistic infections (which embrace tuberculosis and other infections that occur when resistance to disease is lowered) neurological infections (including viral meningitis) eye infections bacterial infections diverticulitis (inflammation and an infection of the massive intestine) cancer most cancers that affects the lymph system melanoma immune problems that could affect the lungs, pores and skin and lymph nodes (most commonly presenting as sarcoidosis) vasculitis (irritation of blood vessels) tremor (shaking) neuropathy (dysfunction of the nerves) stroke hearing loss, buzzing sensation of coronary heart beating irregularly corresponding to skipped beats heart problems that can cause shortness of breath or ankle swelling coronary heart attack a sac within the wall of a significant artery, inflammation and clot of a vein; blockage of a blood vessel lung ailments causing shortness of breath (including inflammation) pulmonary embolism (blockage in an artery of the lung) pleural effusion (irregular collection of fluid in the pleural space) irritation of the pancreas which causes extreme pain within the abdomen and back difficulty in swallowing facial oedema (swelling of the face) gallbladder inflammation, gallbladder stones fatty liver evening sweats scar abnormal muscle breakdown 483 systemic lupus erythematosus (together with irritation of pores and skin, heart, lung, joints and different organ systems) sleep interruptions impotence inflammations Rare (may affect as much as 1 in 1,000 people) leukaemia (most cancers affecting the blood and bone marrow) extreme allergic response with shock multiple sclerosis nerve disorders (similar to eye nerve irritation and Guillain-Barre syndrome that will cause muscle weak point, irregular sensations, tingling within the arms and higher body) heart stops pumping pulmonary fibrosis (scarring of the lung) intestinal perforation (gap in the gut) hepatitis reactivation of hepatitis B autoimmune hepatitis (irritation of the liver caused by the body's personal immune system) cutaneous vasculitis (irritation of blood vessels within the skin) Stevens-Johnson syndrome (early symptoms embrace malaise, fever, headache and rash) facial oedema (swelling of the face) associated with allergic reactions erythema multiforme (inflammatory skin rash) lupus-like syndrome angioedema (localized swelling of the pores and skin) lichenoid skin reaction (itchy reddish-purple pores and skin rash) Not recognized (frequency can't be estimated from the obtainable knowledge) hepatosplenic T-cell lymphoma (a rare blood cancer that is often deadly) Merkel cell carcinoma (a kind of skin cancer) liver failure worsening of a condition known as dermatomyositis (seen as a pores and skin rash accompanying muscle weakness) Some unwanted side effects noticed with Humira could not have signs and should solely be discovered by way of blood tests. 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