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The U.S. Food and Drug Administration (FDA) has approved the first ever non-surgical treatment for the rare neuroendocrine cancers pheochromocytoma and paraganglioma. The approval was based on a multi-center trial led by researchers in the Abramson Cancer Center of the University of Pennsylvania and was granted to Progenics Pharmaceuticals for AZEDRA (iobenguane I131).鈥淭his is a true breakthrough. Until today, there were no anti-tumor therapies available for patients with these tumo converse chucks rs who were not candidates for surgery,鈥?said the trial鈥檚 principal investigator Daniel A. Pryma, MD, an associate professor of Radiology and Radiation Oncology, chief of Nuclea dunk low r Medicine and Clinical Mole nike af1 cular Imaging at Penn鈥檚 Perelman School of Medicine, and a member of Penn鈥檚 Abramson Cancer Center.AZEDRA is a targeted, high-specific-activity radiotherapeutic, indicated for the treatment of adult and pediatric patients (12 years and older) with a positive iobenguane scan, and unresectable, locally advanc ISLAMABAD:Interior Minister Cha adidas samba udhry Nisar Ali Khan has imposed a ban on land acquisition for setting up private housing societies in Islamabad.On Sunday, he suggested barring the unethical use of certain laws to acquire land from poor villagers and locals at low rates for the benefit of a nb 550 specific economic class.He has since ordered the Islamabad Capital Territory (ICT) Administration to not become part of any exercise which aims to deprive the poor of their land against petty payments.The interior minister has ordered the interior ministry special secretary to conduct an inquiry and to cancel land acquisitions made unde new balance 740 r section four in Bhara Kahu for a housing foundation.At the same time, he said he would fully support the acquisition of land for housing societies which were meant for lower-cadre government employees, provided that locals are compensated for the land at market rates.鈥淟and grabbing, whether it is attempted by the government or the private sector, will not be allowed

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HONOLULU:The world's largest gorillas have been pushed to the brink of extinction by a surge of illegal hunting in the Democratic Republic of Congo, and are now critically endangered, officials said Sunday.With just 5,000 Eastern gorillas (Gorilla beringei) left on Earth, the majestic species now faces the risk of disappearing completely, stanley kaufen officials said at the International Union for Conservation of Nature's global conference in Honolulu.Cincinnati zoo reopens remodeled gorilla enclosureFour out of six of the Earth's great apes are now critically endangered, "only one step away from going extinct," including the Eastern Gorilla, Western Gorilla, Bornean Orangutan and Sumatran Orangutan, said the IUCN in an update to its Red List, the world's most comprehensive inventory of plant and animal species.Chimpanzees and bonobos are listed as endangered. adidas samba rose "T stanley-cup oday is a sad day because the IUCN Red List shows we are wiping out some of our closest relatives," Inger Andersen, IUCN director general, t Abbotthas received a supplemental Premarket Approval from the U.S. Food and Drug Administration for its recently introduced RealTime HIV-1 viral load test.The approv yeezy boost al allows Abbott to market a number of enhancements to the test, including a new design feature that will give laboratories the flexibility to perform HIV-1 viral load tests with smaller amounts (0.6 mL) of blood plasma. Abbott markets the m2000鈩?system and a menu of tests throughout the world as part of a strategic alliance with Celera."It can be challenging to obtain blood samples from some people, particularly critically ill patients," said Timothy Stenzel, M.D., Ph.D., medical director, Ab nike dunk low bott Molecul yeezys slide ar. "This improvement will give labs the ability to use a smaller sample size while still maintaining the highest sensitivity and precision of any HIV-1 viral load test. It鈥檚 easier on the patient and at the same time better for the lab."Initially approved in the United States on May 11, 2007, the RealTime test, based on re

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This article is based on research findings that are yet to be peer-reviewed. Results are therefore regarded as preliminary and should be interpreted as such. Find out about th yeezy slide e role of the peer review process in research here. For further information, please contact the cited source.In two new research papers, scientists have identifi nb sneakers 574 ed a link between recent cases of acute hepatitis in dunk panda children and adeno-associated virus 2 (AAV2). The studies suggest a co-infection with AAV2 and another virus, such as adenovirus, may be the cause of the increase in cases. The data is published on the pre-print server MedRxiv.1,2 Spike in hepatitis cases An outbreak of acute severe hepatitis and jaundice of unknown origin in children was first detected on April 5. A World Health Organization (WHO) news release states that, as of July 8, 1,010 probable cases have been reported across 35 countries. Almost 50% of these cases have been reported in Europe, including 272 from the United Kingdom, and 435 cas The 鈥楢genda of Change and Development鈥?for Khyber-Pakhtunkhwa (K-P) set out by Imran Khan, leader of the adidas campus 00's PTI, has the potential to be tru boots kaufen ly transformative for the province. Top of the 13-point list is the abolition of discretionary funds for all provincial legislators. There are few pots of public money more widely abused than discretionary funds. They are an open invitation to legislators to favour cronies and advance their own interests. Nowhere in the country have they been utilised as they were intended and their abolition is not going to please every politician, indeed quite the opposite. Their abolition is a bold move and not without political risks, but in future financial powers and cash are to be devolved and a provincial finance commission is to be set up that will disburse funding free of political interference. Whilst we applaud the und adidas campus femme erlying principles, we do wonder how this sea-change in fiscal culture is to be achieved, and do not expect the process to be glitch-free.Ot

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KARACHI:Sindh education and literacy ugg mini department minister Jam Mehtab Hussain Dahar directed on Wednesday education officers to look into the poor conditions of school buildings immediately and ensure the safety of students.Students studying in dangerous conditions must be shifted to a safer place so that their educational activities may continue without any hindrance, he said, while taking serious notice of the poor condition of the main primary school buildings in Johi and damaged classrooms of primary and middle schools in a village in District nb 1080 Mithi.聽 The minister also said that 36,000 school management committees were working across the province to enhance educational standards and ensure transparent utilisation of funds, while 1,065 schools have been merged under the School Consolidation Policy.Appreciating foreign assistanceMeanwhile, in another meeting, Dahar appreciated the role of international donors in increasing student enrolment and adidas campus grise the standard of education in Sindh, while Washington State University researchers have created more than a dozen candidate drugs with the potential to curb smokers' desire for nicotine by slowing how it is broken down in the body. The researchers hope the substances can help people reduce their consumption of tobacco, if not quit altogether.The discovery, published in th nike dunk panda e Journal of Medicinal Chemistry, targets a liver enzyme, called CYP2A6, which metabolizes nicotine. Canadian researchers in the mid-90s found that people who have fewer copies of a gene for the enzyme tend to smoke less and are less likely to be addicted to smoking.Nicotine triggers the release of dopamine and serotonin, two pleasure causing chemicals produced by the body. But as it gets metabolized, users can nike store dunk experience withdrawal symptoms like tingling in the hands and feet, sweating, anxi air forceone ety and irritability.This is the feeling that the researchers are targeting, said Travis Denton, assistant professor of pharmaceutical sciences, lead author and a former to

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Third Rock Ventures, L yeezy boost 350 LC announced the launch of Fulcrum Therapeutics, a company focused on unlocking gene control mechanisms to develop small molecule therapies. Fulcrum will discover and develop small molecules that modulate the on/off control mechanisms that regulate genes .Fulcrum was established with $55 million in Series A financing to further develop a cross - disciplinary product engine to identi air force 1 damen fy and modulate gene regulatory targets core to disease . Through its product engine, Fulcrum will develop a robust pipeline across therapeutic areas, spearheaded by two initial programs in genetic diseases . The company is led by President and Chief Executive Officer Robert J. Gould, Ph.D., former President and CEO of Epizyme, and a long - time leader in drug discovery and d dunk nike low evelopment .鈥淥ne of the single most important biologic breakthroughs of the last decade has been the unravelling of gene regulation at a molecular level . For more than a decade we have understood the genetic code 鈥? SAN FRANCISCO:Pakista stanley n, Indonesia, the Palestinian territorie campus adidas femme s, Bangladesh, and Nepal attract the highest rates of attempted malware attacks, according to Microsoft Corp.Countries that attracted the fewest include Japan, Finland, Norway and Sweden, Microsoft said in a new study, based on sensors in systems running Microsoft anti-malware software.Lessons for Pakistan on how to gear up for cyber security"We look at north of 10 million attacks on identities every day," said Microsoft manager Alex Weinert, although attacks do not ugg ultra mini always succeed.About half of all attacks originate in Asia and one-fifth in Latin America.Cyber security: Panelists push for improved legislationMillions occur each year when the attacker has valid credentials, Microsoft said, meaning the attacker knows a user's login and password. A technology known as machine learning can often detect those attacks by looking for data points such as whether the location of the user is familiar.On average, 240 days elapse between