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Mxrc Study in Mice Uncovers Pathway Critical for UV-Induced Melanoma
Adolescent marijuana use may alter how neurons function in brain areas engaged in decision-making, planning and self-control, accordin <a href=https://www.adidas-yeezy.de>yeezy damen</a> g to researchers at the University of Illinois at Chicago.The findings, which were presented at Neuroscience 2018, the annual meeting of the Society for Neuroscience, are the result of an animal model study focused on the structural development of the prefrontal cortex, or PFC, which <a href=https://www.yeezyy.at>yeezy schuh</a> controls high-level cognitive functions.Within the PFC, a support structure called the pe <a href=https://www.nike-dunk.it>dunk high</a> rineuronal net forms a lattice of proteins around inhibitory cells, helping to secure their connections with excitatory neurons and regulate PFC activity. Perineuronal net formation is sensitive to drug use, but the effects of marijuana are not known.To investigate how adolescent marijuana use affects perineuronal nets in the PFC, the UIC researchers gave adolescent rats a synthetic cannabinoid which was similar to THC, the main psychoactive compound in marijuana, for one day, 10 days, o PESHAWAR:The Khyber-P <a href=https://www.nbbalance.it>new balance 480</a> akhtunkhwa (K-P) government <a href=https://www.adidas-samba-adidas.it>adidas samba</a> 鈥檚 law department has duly vetted the proposed amendments of the health department to the NWFP Drug Sale Rules 1982. The amendments will soon be sent to K-P Chief Minister Pervez Khattak for final approval.According to an official statement issued by the health ministry on Saturday, the proposed amendments laid down some strict criteria for drug sale outlets, including medical stores, pharmacies and who <a href=https://www.nbbalance.it>nb 530</a> lesale stores in the province.It has been held compulsory for聽 the salesperson of a medical store and pharmacy to be a graduate or diploma holder in pharmacy with a valid licence from the concerned regulatory body whereas the salesperson of a wholesale store must not be less than a pharmacy graduate having a valid licence.As long as a medical store, pharmacy shop or wholesale store remains open, the presence of a salesperson with the aforesaid prescribed qualification will be a must, it read and added that pharma companies will have to supp
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Wdzo To Wilt or Not to Wilt
KARACHI:Even if citizens try to keep their streets clean, they still have to dump their garbage at some place. Collection and disposal of garbage is a major issue being faced by the public, which cannot be solved without the government's help.This was the general theme of a discussion on Karachi's garbage crisis by civic experts at the Aga Khan University on Thursday.Garbage stays as CM鈥檚 deadline expiresPiles of garbage lying unattended in the streets, parks, playgrounds, alleyways and the coast speaks volumes about the government apathy in deal <a href=https://www.adidas-samba-adidas.fr>samba adidas og</a> ing with the menace of waste disposal, agreed urban planners."Sinc <a href=https://www.nbbalance.it>new balance 991</a> e there is a total vacuum from the government's side, we should cr <a href=https://www.adidas-samba-adidas.it>adidas samba adidas</a> eate a network of NGOs, civil society and communities to solve the garbage problem," remarked urban planner Farhan Anwar.Sharing data from a book, associate professor of urban studies at the department of social sciences and liberal arts, Institute of Business Administration, Nausheen Anwar, said that among 20 wast Just as bright light can illuminate the depths of a darkened room, researchers in Japan <a href=https://www.adidas-yeezy.de>adidas yeezys</a> have found that blue light can be <a href=https://www.yeezyy.at>yeezy slide</a> used to probe the depths of the eye and uncover areas affected by diabetic retinopathy (DR), a leading cause of blindness. In a new study published inAsia-Pacific Journal of Ophthalmology, researchers from Tokyo Medical and Dental University (TMDU) have revealed that blue images obtained by multicolor widefield scanning laser ophthalmoscopy (SLO) may be used to identify areas of DR-induced damag <a href=https://www.nikeairforces.de>air forces</a> e in a more extensive portion of the eye compared with previous methods. Current eye imaging methods include fluorescein angiogram, which involves the injection of dye into the eye. SLO is a non-invasive approach that does not require dye, and multicolor widefield SLO represents an advancement of this technique in which red, blue, and green lasers are used to simultaneously capture images of a wide portion of the eye. Previous research has shown that blue images captured by c
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Kxmf New Method May Help Develop New Drugs Without Side Effects
GANGNAULI , INDIA:As large swathes of drought-devastated India desperately wait for the monsoon rains to arrive, one village in the dry, hot north is flush with water.But this farming area's bountiful water supplies are feared contaminated with heavy metals, undersc <a href=https://www.adidascampus.com.de>adidas campus 80s</a> oring the profound challenges facing the world's second most populous nation.From toxic pollution o <a href=https://www.nbbalance.fr>new balance pour femme</a> f rivers and lakes to contamination of groundwater supplies, together with chronic shortages in drought-hit districts, India's water challenges are acute.MQM leader warns of riots if water crisis not addressedIn Gangnauli village, residents suspect their groundwater has been polluted by waste from local industries."The children complain of stomach pains and skin problems and I fear for their health," Divya Rathi says as she watches her daughter play with buckets of water in her yard in Gangnauli in Uttar Pradesh state."We need the gover <a href=https://www.nbbalance.fr>new balance</a> nment to do something about this," said the 25-year-old, adding she could not afford the expe SIRS-Lab, has announced the inclusion of the first patient in a 1000-patient clinical study evaluating their molecular pathogen test VYOO. The multicenter trial, performe <a href=https://www.nike-dunk.it>dunk nike store</a> d in 11 key centers across Germany and initiated in February 2011, will deliver data ab <a href=https://www.adidas-yeezys.fr>adidas yeezy</a> out the utility of the PCR test compared to conventional methods to identify microbes in ICU patients with suspected sepsis.Sepsis is one of the leading causes of death in hospitals. Every year, more than 60,000 patients die from sepsis in Germany alone. It occurs when microbes enter the bloodstream and trigger a severe inflammatory response by the patient麓s body. This is often life-threatening, and the search for the appropriate antibiotic or antifungal treatment can be a race against time.Traditional diagnostic methods can take several days to complete, and often miss the infection. With molecular diagnostics like the VYOO test, the microbe can be identif <a href=https://www.nike-dunk.es>nike dunkpanda</a> ied within hours, allowing rapid tailoring of the patient's therapy.The bigges
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Zauc Are 鈥淥mic鈥?Studies the Future of Precision Medicine in Asthma
MIT and Harvard University chemists have discovered <a href=https://www.adidas-yeezy.de>adidas yeezys boost</a> the structure of an unusual bacterial enzyme that can break down an amino acid found in collagen, which is the most abundant protein in the human body.The enzyme, <a href=https://www.adidas-yeezy.it>yeezy boost</a> known as hydroxy-L-proline dehydratase (HypD), has been found in a few hundred species of bacteria that live in the human gut, including Clostridioides difficile. The enzyme performs a novel chemical reaction that dismantles hydroxy-L-proline, the molecule that gives collagen its tough, triple-helix structure.Now that researchers know the structure o <a href=https://www.adidas-yeezys.es>yeezys</a> f the enzyme, they can try to develop drugs that inhibit it. Such a drug could be useful in treating C. difficile infections, which are resistant to many existing antibiotics.鈥淭his is very exciting because this enzyme doesn鈥檛 exist in humans, so it could be a potential target,鈥?says Catherine Drennan, an MIT professor of chemistry and biology and a Howard Hughes Medical Institute Investigator. 鈥淚f you could potentially inhibit th ISLAMABAD:The Second Rehabilitation Project of Warsak Hydel Power Project, which is to be executed by the Water and Power Development Authority (Wapda), will help the plant regain its generation capacity, which has decreased to 193MW from 243MW due to aging of the electro-mechanical equipment.The rehabilitation work, planned to be carried out with an approved PC-I <a href=https://www.adidascampus.com.de>adidas campus wei脽</a> cost of Rs22.25 billion,聽 aims to overcome the aging problems, regain the capacity loss of 50MW with reliable annual energy generation of 1.14 billion units, upgrade and modernise the old system and achieve another life cycle of 30 to 40 years, officials told APP on Friday.They said that German financial institution KfW an <a href=https://www.inkwiz.se>ugg boots damen</a> d French Development Agency (AFD) were providing loan to <a href=https://www.nbbalance.es>nb 574</a> the tune of 40 million Euro each, while European Investment Bank (EIB) was giving 50 million Euro.Published in The Express Tribune, December 10th, 2016.Like聽Business on Facebook, follow @TribuneBiz聽on Twitter to stay informed and join in the conversati
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Obxn Sindh gears up for its very own property survey
Avid Bioservices, Inc., a leading provider of integrated biomanufacturing services and a subsidiary of Peregrine Pharmaceuticals, <a href=https://www.asicsgel.de>asics gel kayano</a> Inc. (NASDAQ: PPHM), today announced it has secured a biomanufacturing contract to supply clinical material over the coming year to Affitech A/S (NASDAQ OMX: AFFI), the antibody medicines company. The initial contract for committed services provides for several large-scale cGMP manufacturing runs as well as other cGMP-related services.鈥淕iven our long-ter <a href=https://www.adidas-yeezys.fr>adidas yeezys</a> m relationship, Avid i <a href=https://www.nike-dunks.de>nike dunken low</a> s an ideal partner for providing biomanufacturing services for our fully human antibody AT001/r84, as they have direct experience with Peregrine鈥檚 anti-VEGF technology platform as well as this novel antibody we discovered from this technology,鈥?said Martin Welschof, Managing Director of Affitech. 鈥淥ver the coming year, we look forward to having Avid鈥檚 support as we expedite our clinical development plans for AT001/r84 for select growing pharmaceutical markets.鈥滱bout AT001/r84 AT001/r84 i QUETTA:In its ongoing campaign against corruption, the country鈥檚 premier anti-graft watchdog has arrested a former chairman of the Balochistan Public Service Commission for alleged misuse of authority and financial corruption.Ashraf <a href=https://www.valela.at>uggs hausschuhe</a> Magsi was detained from his residence Monday morning, according to a spokesperson for the National Accountability Bureau (NAB) Balochistan.鈥淢agsi had issued fake certificates to his two daughters, a son and a woman for acquiring key posts in government departments,鈥?he added. He a <a href=https://www.nbbalance.it>new balance uomo</a> lso pocketed millions of rupees in bribes for issuing such fake certificates to ineligible candidates.Balochis <a href=https://www.nbbalance.es>nb 9060</a> tan Governor Muham卢mad Khan Achakzai had sacked Magsi six months ago on corruption charges. The suspect has been shifted to a NAB cell for further investigation.The NAB spokesperson said Magsi鈥檚 two former deputies, who are already in the watchdog鈥檚 custody, were also presented before an accountability court on Monday.鈥淎bdul Waheed and Niaz Kakar had been arrested for takin
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Pevd CPEC will see several govts before its completion: President Mamnoon
NMT Pharmaceuticals Pte Ltd (NMT Pharma) has announced that it has signed a legally binding Letter of Intent <a href=https://www.jordann.at>damen jordans</a> with US-based CAO Pharmaceuticals Inc. (CAO Pharma) for acquiring an exclusive worldwide license right to further develop and market an anti-cancer drug CZ-48 co-developed by CAO Pharma and NMT Pharma.NMT Pharma and CAO Pharma will enter into agreements that would secure funding needed by CAO Pharma to continue to operate and conduct clinical trials in US. The collaboration is subjected to, among with other requirements, satisfactory completion of due diligence and the execution of a definitive agreement.CZ-48 is an analogue of camptothec <a href=https://www.nike-dunk.it>nike dunk uomo</a> in which is <a href=https://www.yeezyy.at>yeezys 350</a> stable and resistant to inactivation while circulating in human bloodstream. This topoisomerase I inhibitor only becomes active when entering in tumor cells. Based on preclinical and previous Phase I clinical trial data, CZ-48 has very low toxicity and mild side effects.CAO Pharma and NMT Pharma have improved the formulation of CZ-48 ISLAMABAD:A Senate panel on Tuesday called upon the Capital Development Authority (CDA) to test the water being supplied to the capital to ensure the residents are being provided with clean drinking water.A meeting of the Senate Standing Committee on Science and Technology on Tuesday included a briefing by Pakistan Standard Quality Control Authority (PSQCA) on the quality of bottled w <a href=https://www.nbbalance.it>nb balance</a> ater and packaged milk, coordination among regulators including PSQCA, Pakistan Council of Research in Water Resources (PCRWR) and CDA regarding supply of clean drinking water to the residents of Islamabad besides of safe drinking water project of PCRWR.Noting that no work had been done to check the quality of milk in Pakistan, Senator Mian Attique Sheikh said that he had raised the issue of shampoo and othe <a href=https://www.nbbalance.es>nb balance</a> r harmful things mixed in milk.Senator Azam Khan Swati said that when he was minister the PSQCA was a corrupt organisation and sought details about t <a href=https://www.inkwiz.se>uggs hausschuhe</a> he Rs980 million in fines recovered during his tenure

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