Jhpe Understanding Breast Cancer Immune Escape May Lead to Treatment Pathway
Scientists at the National Institutes of Health, and their colleagues, have discovered that a gene called BACH2 may play a central role in the development of diverse allergic and autoimmune diseases, such as multiple sclerosis, asthma, Crohn's disease, celiac disease, and type-1 diabetes.In autoimmune diseases, the immune system attacks normal cells and tissues in the body that are generally recognized as 鈥渟elf鈥?and
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do not normally trigger immune responses. Autoimmunity can occur in infectious diseases and cancer.The results of previous research had shown that
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people with minor variations in the BACH2 gene often develop allergic or autoimmune diseases, and that a common factor in these diseases is a compromised immune system.In thi
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s study in mice, the Bach2 gene was found to be a critical regulator of the immune system鈥檚 reactivity.The study, headed by researchers at the National Cancer Institute (NCI) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS BAHAWALPUR:Government employees staged a protest for not regularising the contractual employees of water management on Monday.While addressing the demonstration, protesters said more than 1,800 employe
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es of the water managemen
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t were still waiting for job regularisation across the province. They said on the orders of Punjab chief minister, hundreds of contractual employees were regularised, while water management staff was neglected. They said earlier on April 4, 2010 former provincial agriculture minister Ahmad Ali promised to regularise the employees within a week but in vain. They said the poor employees had bee
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n waiting to get their jobs regularised for the last 12 years.They lamented the agriculture secretary ordered to lay off these workers by June 2017. They threatened the agitated employees of water management will commit suicide along with their families in front of the CM house if any employee was sacked.Published in The Express Tribune, October 4th, 2016.